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Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy

Nancy E. Scott, Serin Edwin Erayil, Susan E Kline, Anna Selmecki

2023Antimicrobial Agents and Chemotherapy31 citationsDOIOpen Access PDF

Abstract

Candida ( Clavispora ) lusitaniae is a rare, emerging non- albicans Candida species that can cause life-threatening invasive infections, spread within hospital settings, and rapidly acquire antifungal drug resistance, including multidrug resistance. The frequency and spectrum of mutations causing antifungal drug resistance in C. lusitaniae are poorly understood.

Topics & Concepts

MicafunginFluconazoleEchinocandinDrug resistanceAntifungal drugMultiple drug resistanceBiologyMicrobiologyMedicineCandida albicansAntifungalAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases
Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy | Litcius