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Mechanisms for licensing origins of DNA replication in eukaryotic cells

Bruce Stillman, John F.X. Diffley, Janet Iwasa

2025Nature Structural & Molecular Biology11 citationsDOI

Topics & Concepts

Origin recognition complexPre-replication complexDNA replication factor CDT1Random hexamerEukaryotic DNA replicationDNA replicationControl of chromosome duplicationLicensing factorOrigin of replicationBiologyCell biologyReplication factor CS phaseSaccharomyces cerevisiaeGeneticsCell cycleDNAComputational biologyGeneMolecular biologyDNA Repair MechanismsMicrotubule and mitosis dynamicsBacterial Genetics and Biotechnology
Mechanisms for licensing origins of DNA replication in eukaryotic cells | Litcius