Organocatalytic asymmetric synthesis of β,β-diaryl ketones <i>via</i> one-pot tandem dehydration/1,6-addition/decarboxylation transformation of β-keto acids and 4-hydroxybenzyl alcohols
Jiapan Niu, Jing Nie, Shen Li, Jun‐An Ma
Abstract
An one-pot tandem dehydration/1,6-addition/decarboxylation transformation of β-keto acids and 4-hydroxybenzyl alcohols provides an metal-free protocol to chiral β,β-diaryl ketones.
Topics & Concepts
DecarboxylationChemistryDehydrationTandemTransformation (genetics)Organic chemistryStereochemistryCombinatorial chemistryCatalysisBiochemistryComposite materialGeneMaterials scienceSynthesis of Indole DerivativesAsymmetric Synthesis and CatalysisAxial and Atropisomeric Chirality Synthesis