APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

Axel Montagne, Angeliki M. Nikolakopoulou, Mikko T. Huuskonen, Abhay P. Sagare, Erica J. Lawson, Divna Lazić, Sanket Rege, Alexandra Grond, Edward Zúñiga, Samuel Barnes, Jacob Prince, Meghana Sagare, Ching-Ju Hsu, Mary Jo LaDu, Russell E. Jacobs, Berislav V. Zloković