Litcius/Paper detail

Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death

Pavel Zakharov, Chanchal Sur Chowdhury, Orion J. Peterson, Brady Barron, Anthony N. Vomund, Laurent Gorvel, Emil R. Unanue, Eynav Klechevsky, Xiaoxiao Wan, Kodi S. Ravichandran

2025Nature7 citationsDOIOpen Access PDF

Topics & Concepts

EfferocytosisImmune systemNOD micePancreatic isletsIsletEx vivoPancreasNodBiologyCell biologyIn vivoPhagocytosisMacrophageApoptosisCancer researchImmunologyPhenotypeInnate immune systemReprogrammingCellAcquired immune systemProgrammed cell deathCell typeAutoimmune diseaseGlucose homeostasisCytotoxic T cellAutoimmunityType 1 diabetesT cellHomeostasisMedicineInsulitisDiabetes mellitusPancreatic function and diabetesPhagocytosis and Immune RegulationDiabetes and associated disorders