Genetic ablation of Pim1 or pharmacologic inhibition with TP-3654 ameliorates myelofibrosis in murine models
Avik Dutta, Dipmoy Nath, Yue Yang, Bao T. Le, Mohammad Ferdous-Ur Rahman, Patrick Faughnan, Zhenjia Wang, Matthew Stuver, Rong‐Quan He, Wuwei Tan, R. Hutchison, Jason M. Foulks, Steven L. Warner, Chongzhi Zang, Golam Mohi
Topics & Concepts
MyelofibrosisRuxolitinibPIM1Bone marrowHaematopoiesisMyeloproliferative neoplasmGranulocytosisBiologyCancer researchImmunologyMedicineStem cellGranulocyteGeneticsSerinePhosphorylationMyeloproliferative Neoplasms: Diagnosis and TreatmentCancer Mechanisms and TherapyMultiple Myeloma Research and Treatments