Recent progress in chemoenzymatic synthesis of human glycans
Shengzhou Ma, Jinhua Gao, Yinping Tian, Liuqing Wen
Abstract
-linked glycans, human milk oligosaccharides, and glycosaminoglycans. Thus, we provide an overview of recent chemoenzymatic synthetic designs and applications for synthesizing complex human glycans, along with insights into the limitations and perspectives of the current methods.
Topics & Concepts
GlycanComputational biologyChemistryBiologyBiochemistryGlycoproteinGlycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisUbiquitin and proteasome pathways