Litcius/Paper detail

FDA Eliminates the Clozapine REMS—What Comes Next?

Deanna L. Kelly, John M. Kane, Raymond C. Love, Robert O. Cotes

2025JAMA Psychiatry13 citationsDOI

Abstract

This Viewpoint provides suggestions to address challenges after elimination of the Clozapine Risk Evaluation and Mitigation Strategies (REMS) system by the US Food and Drug Administration (FDA).

Topics & Concepts

ClozapineFood and drug administrationMedicineDrugPharmacologyIntensive care medicineSchizophrenia (object-oriented programming)PsychiatrySchizophrenia research and treatmentHealth Systems, Economic Evaluations, Quality of LifeMental Health and Psychiatry