PAI-1 Deficiency Promotes NET-mediated Pyroptosis and Ferroptosis during Pseudomonas Aeruginosa-induced Acute Lung Injury by Regulating the PI3K/MAPK/AKT Axis
Nurbiya Aji, Linlin Wang, Sijiao Wang, Ting Pan, Juan Song, Cuicui Chen, Lu Wang, Nana Feng, Xinjun Tang, Yuanlin Song
Topics & Concepts
PyroptosisProtein kinase BProinflammatory cytokinePI3K/AKT/mTOR pathwayInflammationMAPK/ERK pathwayNeutrophil extracellular trapsChemistryImmunologyBronchoalveolar lavageMedicineLungCancer researchInflammasomeApoptosisSignal transductionInternal medicineBiochemistryNeutrophil, Myeloperoxidase and Oxidative MechanismsInflammasome and immune disordersImmune cells in cancer