Litcius/Paper detail

Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment

Yangliu Xia, Jingjing Wang, Shi-Yang Li, Yong Liu, Frank J. Gonzalez, Ping Wang, Guang‐Bo Ge

2020Bioorganic & Medicinal Chemistry30 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryCoumarinInhibitory postsynaptic potentialStereochemistryDocking (animal)IC50Structure–activity relationshipPharmacologyTrifluoromethylIn vitroBiochemistryAlkylMedicineBiologyNeuroscienceOrganic chemistryNursingClick Chemistry and ApplicationsSynthesis and biological activitySynthesis and Biological Evaluation