Antidepressant actions of ketamine engage cell-specific translation via eIF4E
Argel Aguilar‐Valles, Danilo De Gregorio, Edna Matta‐Camacho, Mohammad J. Eslamizade, Abdessattar Khlaifia, Agnieszka Skaleka, Martha López-Canul, Angélica Torres‐Berrío, Sara Bermudez, Gareth M. Rurak, Stephanie Simard, Natalina Salmaso, Gabriella Gobbi, Jean‐Claude Lacaille, Nahum Sonenberg
Topics & Concepts
KetamineAntidepressantmTORC1Inhibitory postsynaptic potentialExcitatory postsynaptic potentialNeurosciencePharmacologyBiologyChemistryHippocampusPI3K/AKT/mTOR pathwayCell biologySignal transductionTreatment of Major DepressionNeuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling