Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells
Yao Liu, Yongqi Zhen, Guan Wang, Gaoxia Yang, Leilei Fu, Bo Liu, Liang Ouyang
Topics & Concepts
ChemistryProteolysisProteasomeProtein degradationCancer researchProteasome inhibitorApoptosisSmall moleculeProtein kinase ACancerKinaseCancer cellCell biologyBiochemistryBiologyInternal medicineEnzymeMedicineProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis