Mechanistic insights into AMPK-SIRT3 positive feedback loop-mediated chondrocyte mitochondrial quality control in osteoarthritis pathogenesis
Yang Chen, Yongyao Wu, Haibo Si, Yanrong Lu, Bin Shen
Topics & Concepts
SIRT3AMPKOsteoarthritisPathogenesisControl (management)MedicineBioinformaticsCell biologySirtuinBiologyComputer scienceInternal medicineGeneGeneticsPathologyPhosphorylationAlternative medicineProtein kinase AArtificial intelligenceAcetylationOsteoarthritis Treatment and MechanismsAdipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors