Colorectal Cancer Surveillance With Circulating Tumor DNA Assay
Alan P. Venook
Abstract
No area of cancer medicine has advanced as rapidly as molecular-based diagnostics, which have become so sensitive and specific that we now have the capacity to identify bits of tumor DNA circulating in the bloodstream (ctDNA). One such assay, Signatera (Natera), is informed by wholeexome sequencing of an individual's primary tumor, so its specificity is nearly certain.
Topics & Concepts
Colorectal cancerCancerCirculating tumor DNACancer researchMedicineOncologyInternal medicineCancer Genomics and DiagnosticsColorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer