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Modified histidine containing amphipathic ultrashort antifungal peptide, His[2-p-(n-butyl)phenyl]-Trp-Arg-OMe exhibits potent anticryptococcal activity

Krishna K. Sharma, Ravi Kant Ravi, Indresh Kumar Maurya, Akshay Kapadia, Shabana I. Khan, Vinod Kumar, Kulbhushan Tikoo, Rahul Jain

2021European Journal of Medicinal Chemistry29 citationsDOI

Topics & Concepts

ChemistryPeptideCytotoxicityStereochemistryHistidineCryptococcus neoformansImidazoleMoietyBiological activityAmphiphileBiochemistryIn vitroAmino acidOrganic chemistryMicrobiologyBiologyCopolymerPolymerAntimicrobial Peptides and ActivitiesChemical Synthesis and AnalysisBiochemical and Structural Characterization
Modified histidine containing amphipathic ultrashort antifungal peptide, His[2-p-(n-butyl)phenyl]-Trp-Arg-OMe exhibits potent anticryptococcal activity | Litcius