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Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision

Rebecca Ward, Joanna J. Kaylor, Diego Cobice, Dionissia A. Pepe, Eoghan M. McGarrigle, Susan E. Brockerhoff, James B. Hurley, Gabriel H. Travis, Breandán N. Kennedy

2020Journal of Biological Chemistry28 citationsDOIOpen Access PDF

Abstract

) did not eliminate photopic vision in zebrafish. Our findings define molecular and temporal requirements of the nonphotopic or photopic visual cycles for mediating vision in bright light.

Topics & Concepts

Photopic visionVisual phototransductionZebrafishRPE65Scotopic visionRetinaPhotopigmentRetinalRetinoidBiologyCell biologyNeuroscienceRetinal pigment epitheliumBiochemistryRetinoic acidGeneRetinal Development and DisordersRetinal Diseases and TreatmentsRetinoids in leukemia and cellular processes