Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2
Meng Sun, Helin Zhang, Min Jiang, Yan Chai, Jianxun Qi, George F. Gao, Shuguang Tan
Abstract
interactions. The present findings will improve understanding of the molecular assembly of TROP-2 on tumor cells and shed light on future design of biologics for tumor therapy.
Topics & Concepts
ChemistryAntigenMonomerStereochemistryBiophysicsCell biologyBiologyImmunologyPolymerOrganic chemistryMonoclonal and Polyclonal Antibodies ResearchPeptidase Inhibition and AnalysisHER2/EGFR in Cancer Research