Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives
Anna Zerdoug, Marc Le Vée, Shotaro Uehara, Béatrice Lopez, Christophe Chesné, Hiroshi Suemizu, Olivier Fardel
Topics & Concepts
TransporterDrugHuman physiologyPharmacologyClinical chemistryMedicinePharmacokineticsBiologyComputational biologyInternal medicineBiochemistryGeneDrug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesPharmacogenetics and Drug Metabolism