Cirrhosis in Wilson Disease is characterized by Impaired Hepatic Synthesis, Leukopenia and Thrombocytopenia
Haojie Zhong, Ping Xiao, Da Lin, Huimin Zhou, Xing‐Xiang He
Abstract
Background: Patients with Wilson disease (WD) progress to cirrhosis at an early age but have good prognoses. This study aimed to delineate hepatic features in WD patients with or without cirrhosis. Methods: Medical data were retrospectively collected from 27 July 2015 to 27 June 2018. WD patients were divided into two groups based on whether or not they progressed to cirrhosis. Liver function, portal hypertension features and hematocytopenia rates were compared between groups.
Topics & Concepts
MedicineGastroenterologyCirrhosisInternal medicinePortal hypertensionHepatic encephalopathyAscitesOdds ratioLiver functionLeukopeniaChemotherapyTrace Elements in HealthLiver Disease and TransplantationIron Metabolism and Disorders