Improving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden
Vincent Millischer, Granville J. Matheson, Sarah E. Bergen, Brandon J. Coombes, Katja Ponzer, Fredrik Wikström, Karolina Jagiełło, Martin Lundberg, Peter Stenvinkel, Joanna M. Biernacka, Olof Breuer, Lina Martinsson, Mikael Landén, Lena Backlund, Catharina Lavebratt, Martin Schalling
Topics & Concepts
MedicineLithium (medication)CohortRenal functionPopulationInternal medicineBipolar disorderCohort studyPediatricsEnvironmental healthBipolar Disorder and TreatmentGenetic Associations and EpidemiologyPhosphodiesterase function and regulation