Cascade intramolecular rearrangement/cycloaddition of nitrocyclopropane carboxylates with alkynes/alkenes: access to uncommon bi(hetero)cyclic systems
Rohit Kumar Varshnaya, Priyanka Singh, Navpreet Kaur, Prabal Banerjee
Abstract
A straightforward approach for the one-pot synthesis of fused bi(hetero)cyclic systems <italic>via</italic> cascade intramolecular rearrangement/cycloaddition reaction of nitrocyclopropane carboxylates with substituted alkynes/alkenes has been demonstrated.
Topics & Concepts
Intramolecular forceChemistryCycloadditionCascadeCascade reactionMedicinal chemistryCombinatorial chemistryStereochemistryOrganic chemistryCatalysisChromatographyCyclopropane Reaction MechanismsCatalytic Alkyne ReactionsCatalytic C–H Functionalization Methods