Mutation-specific effects of NRAS oncogenes in colorectal cancer cells
Natalia Kuhn, Bertram Klinger, Florian Uhlitz, Anja Sieber, Maria Rivera, Kathleen Klotz‐Noack, Iduna Fichtner, Jens Hoffmann, Nils Blüthgen, Christine S. Falk, Christine Sers, Reinhold Schäfer
Topics & Concepts
Neuroblastoma RAS viral oncogene homologKRASCancer researchPI3K/AKT/mTOR pathwayBiologyColorectal cancerMAPK/ERK pathwayPhenotypeDownregulation and upregulationMutationCancerSignal transductionGeneticsGeneCytokine Signaling Pathways and InteractionsColorectal Cancer Treatments and Studiesinterferon and immune responses