Recent perspectives in clinical development of malaria vaccines
Jack Feehan, Magdalena Plebanski, Vasso Apostolopoulos
Abstract
Malaria vaccine research has progressed significantly, with RTS,S/AS01 and R21/Matrix-M receiving WHO endorsement in 2021 / 2023. These vaccines show promise, but challenges like vaccine adherence, strain variation, and resistance persist, highlighting the need for more effective, broad-reaching interventions.
Topics & Concepts
MalariaVirologyMalaria vaccineComputational biologyMedicineBiologyPlasmodium falciparumImmunologyMalaria Research and ControlMosquito-borne diseases and controlvaccines and immunoinformatics approaches