Activation of alkynes by chalcogen bonding: a Se⋯π interaction catalyzed intramolecular cyclization of 1,6-diynes
Yuanling Pang, Zhiguo Zhao, Yao Wang
Abstract
The activation of the triple bond of alkynes was dominated by transition metals, while it is difficult for organocatalysts to play an effective role in this realm. Herein, we describe the activation of alkynes by chalcogen bonding, and the weak Se⋯π interaction was capable of catalyzing the intramolecular cyclization of 1,6-diynes, thus adding a new capability in the list of supramolecular catalysis.
Topics & Concepts
Intramolecular forceChalcogenCatalysisChemistrySupramolecular chemistryCombinatorial chemistryStereochemistryCrystallographyOrganic chemistryCrystal structureCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsSynthesis and Characterization of Pyrroles