Ball‐Milling‐Enabled Reactivity of Manganese Metal**
William I. Nicholson, Joseph L. Howard, Giuseppina Magri, Alex C. Seastram, Adam Khan, Robert R. A. Bolt, Louis C. Morrill, Emma Richards, Duncan L. Browne
Abstract
Efforts to generate organomanganese reagents under ball-milling conditions have led to the serendipitous discovery that manganese metal can mediate the reductive dimerization of arylidene malonates. The newly uncovered process has been optimized and its mechanism explored using CV measurements, radical trapping experiments, EPR spectroscopy, and solution control reactions. This unique reactivity can also be translated to solution whereupon pre-milling of the manganese is required.
Topics & Concepts
ManganeseReactivity (psychology)ReagentBall millElectron paramagnetic resonanceMetalChemistryCombinatorial chemistryMaterials scienceInorganic chemistryOrganic chemistryMetallurgyNuclear magnetic resonancePathologyPhysicsMedicineAlternative medicineAsymmetric Synthesis and CatalysisCoordination Chemistry and OrganometallicsCatalytic Cross-Coupling Reactions