Dual palladium–photoredox catalyzed chemoselective C–H arylation of phenylureas
Sakamuri Sarath Babu, Muhammad Shahid, Purushothaman Gopinath
Abstract
A highly chemoselective C-H arylation of phenylureas has been accomplished using dual palladium-photoredox catalysis at room temperature without any additives, base or external oxidants. Regioselective C-H arylation of N,N'-diaryl substituted unsymmetrical phenylureas has also been accomplished by a careful choice of aryl groups.
Topics & Concepts
PalladiumCatalysisDual (grammatical number)ChemistryCombinatorial chemistryDual roleChemoselectivityOrganic chemistryArtLiteratureCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques