The impact of Nrf2/HO-1, caspase-3/Bax/Bcl2 and ATF6/IRE1/PERK/GRP78 signaling pathways in the ameliorative effects of morin against methotrexate-induced testicular toxicity in rats
Behçet Varışlı, Cüneyt Çağlayan, Fatih Mehmet Kandemır, Cihan Gür, İbrahim Bayav, Aydın Genç
Topics & Concepts
MorinEndoplasmic reticulumOxidative stressApoptosisSuperoxide dismutaseGlutathioneInflammationEndocrinologyPharmacologyInternal medicineGlutathione peroxidaseUnfolded protein responseCatalaseAntioxidantBiologyChemistryMedicineBiochemistryPathologyEnzymeChemotherapy-induced organ toxicity mitigationAcute Lymphoblastic Leukemia researchDrug-Induced Hepatotoxicity and Protection