Heat inactivation of the severe acute respiratory syndrome coronavirus 2
Christophe Batéjat, Quentin Grassin, Jean‐Claude Manuguerra, India Leclercq
Abstract
Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions.
Topics & Concepts
BiosafetySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Virus inactivationCoronavirusVirologyCoronavirus disease 2019 (COVID-19)Virus2019-20 coronavirus outbreakMedicineChemistryMicrobiologyBiologyInternal medicinePathologyOutbreakDiseaseInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingInfection Control and Ventilation