Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics
Piao Zhou, Wei Shi, Xiao-Yan He, Quanyu Du, Fei Wang, Jing Guo
Abstract
CONTEXT: , saikosaponin D (SSD) has attracted extensive attention. However, no summary studies have been reported on the antitumour effects, toxicity and pharmacokinetics of this potential natural anticancer substance. OBJECTIVE: To analyse and summarise the existing findings regarding to the antitumour effects, toxicity and pharmacokinetics of SSD. MATERIALS AND METHODS: , saikosaponin, saikosaponin D, tumour, toxicity, and pharmacokinetics were used as the keywords. RESULTS: of SSD are still controversial. CONCLUSIONS: antitumour effects and pharmacokinetics of the compound.
Topics & Concepts
PharmacokineticsPharmacologyCardiotoxicityContext (archaeology)MedicineToxicityTraditional medicineBiologyInternal medicinePaleontologyNatural product bioactivities and synthesisBioactive Compounds and Antitumor AgentsNatural Compounds in Disease Treatment