Higher blood urea nitrogen level is independently linked with the presence and severity of neonatal sepsis
Xiaojuan Li, Tiewei Li, Jingjing Wang, Geng Dong, Min Zhang, Zhe Xu, Yidi Hu, Bo Xie, Junmei Yang, Yuewu Wang
Abstract
BACKGROUND: Previous studies have demonstrated that blood urea nitrogen (BUN) is strongly associated with sepsis. However, no data are currently available regarding the association of BUN levels and neonatal sepsis. Thus, this study aimed to investigate the role of BUN in predicting the presence and severity of neonatal sepsis. METHODS: = 188) served as controls. We collected complete clinical and laboratory data were collected. Multivariate logistic regression analysis was performed to identify the potential independent risk factor for neonatal sepsis. Receiver operating characteristic (ROC) curve analysis was used to evaluate the prediction accuracy of BUN in predicting neonatal sepsis. All statistical analyses were performed using the statistical package SPSS 24.0. RESULTS: < .001). CONCLUSION: Higher BUN level is independently linked with the presence and severity of neonatal sepsis.