Fas-threshold signalling in MSCs promotes pancreatic cancer progression and metastasis
Andrea Mohr, Tianyuan Chu, Christopher T. Clarkson, Greg N. Brooke, Vladimir B. Teif, Ralf M. Zwacka
Topics & Concepts
Pancreatic cancerMesenchymal stem cellCCL2Cancer researchMetastasisFas ligandTumor microenvironmentBiologyCancerTumor progressionMedicineChemokineImmunologyApoptosisPathologyInflammationInternal medicineProgrammed cell deathTumor cellsBiochemistryMesenchymal stem cell researchCell death mechanisms and regulationAutophagy in Disease and Therapy