PD-1/PD-L1 checkpoint inhibitors in combination with olaparib display antitumor activity in ovarian cancer patient-derived three-dimensional spheroid cultures
Kathryn M. Appleton, Ashley Elrod, Katy A. Lassahn, Stephen Shuford, Lillia Holmes, Teresa M. DesRochers
Topics & Concepts
OlaparibCytotoxic T cellCancer researchEx vivoImmune systemMedicineIn vivoImmunotherapyT cellImmunologyPharmacologyBiologyPoly ADP ribose polymeraseIn vitroBiochemistryGeneBiotechnologyPolymeraseCancer Immunotherapy and BiomarkersPARP inhibition in cancer therapyCAR-T cell therapy research