Piperlongumine inhibits the progression of osteosarcoma by downregulating the SOCS3/JAK2/STAT3 pathway via miR-30d-5p
Yawei Hu, Xinle Luo, Jianhua Zhou, Shaochu Chen, Ming Gong, Yue Deng, Hao Zhang
Topics & Concepts
Propidium iodideSOCS3ChemistryDownregulation and upregulationApoptosisMTT assayAnnexinCancer researchSTAT3Cell growthTransfectionCell culturemicroRNAMolecular biologyCell biologyBiologyProgrammed cell deathBiochemistryGeneGeneticsPiperaceae Chemical and Biological StudiesCytokine Signaling Pathways and InteractionsCancer, Stress, Anesthesia, and Immune Response