Utilizing Quantitative Proteomics to Identify Species-Specific Protein Therapeutic Targets for the Treatment of Leishmaniasis
Sucheewin Krobthong, Yodying Yingchutrakul, Pawitrabhorn Samutrtai, Atitaya Hitakarun, Suradej Siripattanapipong, Saovanee Leelayoova, Mathirut Mungthin, Kiattawee Choowongkomon
Abstract
analysis of protein's antigenicity revealed that eight proteins had the potential for the development of antigenic molecules. Protein profile information and these antigenic proteins may play key roles in the pathogeny of leishmaniasis and can be used as novel therapeutic targets against leishmaniasis in the future.
Topics & Concepts
LeishmaniaLeishmaniasisProteomicsAntigenicityIn silicoBiologyLeishmania donovaniVisceral leishmaniasisAntigenComputational biologyImmunologyGeneticsParasite hostingGeneComputer scienceWorld Wide WebResearch on Leishmaniasis Studiesvaccines and immunoinformatics approachesTrypanosoma species research and implications