Litcius/Paper detail

Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes

Roberto Silva‐Rojas, Vasugi Nattarayan, Francisco Jaque-Fernández, R. Gómez, Alexia Menuet, David J. Reiss, Marie Goret, Nadia Messaddeq, Valentina M. Lionello, Christine Kretz, Belinda S. Cowling, Vincent Jacquemond, Jocelyn Laporte

2021Molecular Therapy39 citationsDOIOpen Access PDF

Topics & Concepts

DynaminMyocyteAmphiphysinBiologyKnockout mouseCell biologySkeletal musclePhenotypeC2C12RYR1Downregulation and upregulationRyanodine receptorMolecular biologyIntracellularMyogenesisGeneticsGeneReceptorEndocrinologyEndocytosisCellular transport and secretionGenetic Neurodegenerative DiseasesMicrotubule and mitosis dynamics