Olaparib enhances the Resveratrol-mediated apoptosis in breast cancer cells by inhibiting the homologous recombination repair pathway
Saptarshi Sinha, Subhajit Chatterjee, Subarno Paul, Biswajit Das, Somya Ranjan Dash, Chinmay Das, Chanakya Nath Kundu
Topics & Concepts
OlaparibPARP1BiologyPoly ADP ribose polymeraseApoptosisDNA repairCancer researchHomologous recombinationPARP inhibitorCancer cellDNA damageCancerCell cycleSynthetic lethalityTransfectionMolecular biologyDNACell cultureBiochemistryPolymeraseGeneticsPARP inhibition in cancer therapyDNA Repair MechanismsCRISPR and Genetic Engineering