Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization
Qin Qin, Guang Xu, Xiaoyan Zhan, Zhilei Wang, Yan Wang, Hongbin Liu, Xiaorong Hou, Wei Shi, Jianli Ma, Zhaofang Bai, Xiaohe Xiao
Topics & Concepts
InflammasomeAIM2In vivoSecretionCaspase 1ChemistryCell biologyInflammationNLRC4In vitroBiologyImmunologyBiochemistryBiotechnologyInflammasome and immune disordersGout, Hyperuricemia, Uric AcidIL-33, ST2, and ILC Pathways