A bioresponsive diselenide-functionalized hydrogel with cascade catalytic activities for enhanced local starvation- and hypoxia-activated melanoma therapy
Xiaoran Ding, Mingsong Zang, Yujie Zhang, Yongchen Chen, Jingjing Du, An Yan, Jiamei Gu, Yuqi Li, Wei Shu, Jiayun Xu, Hongcheng Sun, Junqiu Liu, Shuangjiang Yu
Topics & Concepts
GlutathioneIntracellularGlucose oxidaseHypoxia (environmental)ChemistryCancer cellReactive oxygen speciesCancer researchGlutathione peroxidasePharmacologyBiochemistryCancerBiologyMedicineOxygenEnzymeInternal medicineOrganic chemistryNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisSulfur Compounds in Biology