Performance evaluation of green and conventional solvents in reversed-phase liquid chromatography based on the separation of non-polar and polar substances
Oktawia Kalisz, Gabriela Hulicka, Marek Tobiszewski, Szymon Bocian
Abstract
This study explored ethanol and dimethyl carbonate as greener alternatives to acetonitrile and methanol in UHPLC separations, demonstrating their effectiveness in achieving comparable performance with reduced environmental risks.
Topics & Concepts
PolarChromatographyChemistryPhase (matter)High-performance liquid chromatographyChemical polarityHydrophilic interaction chromatographyReversed-phase chromatographySeparation (statistics)Organic chemistryPhysicsComputer scienceMachine learningAstronomyAnalytical Chemistry and ChromatographyChromatography in Natural ProductsCrystallization and Solubility Studies