A Highly Selective MNK Inhibitor Rescues Deficits Associated with Fragile X Syndrome in Mice
Tarjani Shukla, June Bryan de la Peña, John M. Perish, Jonathan E. Ploski, Craig R. Stumpf, Kevin R. Webster, Catherine A. Thorn, Zachary T. Campbell
Topics & Concepts
Fragile X syndromeFMR1Protein kinase ANeuroscienceGene silencingSynaptic plasticityKinaseEIF4EBiologyPhosphorylationCell biologyTranslation (biology)Messenger RNAGeneticsGeneFragile xReceptorGenetics and Neurodevelopmental DisordersAutism Spectrum Disorder ResearchChromatin Remodeling and Cancer