Toxicological mechanism of large amount of copper supplementation: Effects on endoplasmic reticulum stress and mitochondria-mediated apoptosis by Nrf2/HO-1 pathway-induced oxidative stress in the porcine myocardium
Quanwei Li, Jianzhao Liao, Kai Zhang, Zhuoying Hu, Hui Zhang, Qingyue Han, Jianying Guo, Lianmei Hu, Jiaqiang Pan, Ying Li, Yuelong Li, Zhaoxin Tang
Topics & Concepts
ChemistryEndoplasmic reticulumOxidative stressApoptosisUnfolded protein responseTUNEL assayMitochondrionCell biologyCytochrome cTerminal deoxynucleotidyl transferaseBiochemistryMolecular biologyBiologyTrace Elements in HealthEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy