The challenges of interrogating adipose tissue extracellular vesicle functions in physiology
Clair Crewe
Abstract
Adipose tissue-derived extracellular vesicles (EVs) are at the center of the budding field of EV signaling in metabolic regulation for their strong regulatory effects on local and systemic metabolism. This essay will highlight seminal studies in adipose tissue EV research, critically assess current adipose tissue EV research strategies and discuss the obstacles the field faces moving forward. Recent developments in adipose tissue-derived extracellular vesicle (EV) research is highlighted, assessing current adipose tissue EV research strategies and obstacles the field faces.
Topics & Concepts
Adipose tissueExtracellular vesicleExtracellular vesiclesExtracellularCell biologyBiologyMicrovesiclesEndocrinologyBiochemistryGenemicroRNAExtracellular vesicles in diseaseCardiovascular Disease and AdiposityAdipokines, Inflammation, and Metabolic Diseases