Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides
Tingting Xu, Chen Wang, Sijie Jiang, Tingting Yang, Xueming Wu
Abstract
-β-glucoside (931.2 μM). Fourteen flavonoids and anthraquinones were used as tentative substrates. Glycosylation positions were located at the C-7, C-3' or C4' hydroxyl groups of flavonoids and C-5 hydroxyl group of anthraquinones. The 3',4'-dihydroxy arrangement played the key role for the antioxidant activity of luteolin.
Topics & Concepts
LuteolinGlycosideChemistryGlucosideGlycosylationAntioxidantStereochemistryOrganic chemistryFlavonoidBiochemistryAlternative medicineMedicinePathologyPhytochemicals and Antioxidant ActivitiesNatural product bioactivities and synthesisPhytochemistry and Biological Activities