MicroRNA-responsive ON-OFF hybrid mRNA switch for precise protein expression control
Kaito Masaki, Yoshihiko Fujita, Hirohide Saito
Abstract
mouse model. This ON-OFF hybrid mRNA switch technology allows for the selective expression of target proteins in designated cells and holds promise for the next generation of mRNA therapeutics.
Topics & Concepts
microRNAMessenger RNACell biologyComputational biologyChemistryComputer scienceBiologyGeneGeneticsRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic Engineering