How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view
Matteo Castelli, Pengrong Yan, Anna Rodina, Chander Singh Digwal, Palak Panchal, Gabriela Chiosis, Elisabetta Moroni, Giorgio Colombo
Topics & Concepts
GlycosylationProteomeMolecular dynamicsChemistryProtein structureProtein–protein interactionComputational biologyLigand (biochemistry)BiophysicsCell biologyBiologyBiochemistryReceptorComputational chemistryEndoplasmic Reticulum Stress and DiseaseProtein Structure and DynamicsCellular transport and secretion