Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection
Laura M. Snell, Wenxi Xu, Diala Abd-Rabbo, Giselle M. Boukhaled, Mengdi Guo, Bethany MacLeod, Heidi Elsaesser, Kebria Hezaveh, Nirmin Alsahafi, Sabelo Lukhele, Sara Nejat, Ramanandan Prabhakaran, Slava Epelman, Tracy L. McGaha, David G. Brooks
Topics & Concepts
Cytotoxic T cellBiologyT cellBlockadeImmune systemImmunologyPD-L1Cell biologyCytokineCancer researchImmunityImmunotherapyReceptorIn vitroBiochemistryImmune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers