Persistent SARS‐CoV‐2 Nucleocapsid Protein Presence in the Intestinal Epithelium of a Pediatric Patient 3 Months After Acute Infection
Dalia Arostegui, Kenny Castro, Steven M. Schwarz, Katherine Vaidy, Simon S. Rabinowitz, Thomas Wallach
Abstract
In addition to the severe impact of acute respiratory disease during the SARS-CoV-2 pandemic, the issue of "Long COVID" illness has impacted large numbers of patients following the initial infection. Wide ranges of Long Covid incidence have been reported, ranging from 30 to 87%. Long COVID has a variety of clinical manifestations, including gastrointestinal symptoms. Here, we report a case of persistent abdominal pain, 3 months following a SARS-CoV-2 diagnosis, associated with chronic colonic inflammation and the presence of mucosal SARS-CoV-2 virions.
Topics & Concepts
MedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Incidence (geometry)Coronavirus disease 2019 (COVID-19)Abdominal painPandemic2019-20 coronavirus outbreakDiseaseInflammationRespiratory systemImmunologyGastroenterologyVirologyInternal medicineInfectious disease (medical specialty)OutbreakOpticsPhysicsLong-Term Effects of COVID-19COVID-19 Clinical Research StudiesInflammasome and immune disorders