Nobiletin targets SREBP1/ACLY to induce autophagy-dependent cell death of gastric cancer cells through PI3K/Akt/mTOR signaling pathway
Menglin Chen, Huai Li, Shanshan Zheng, Junyu Shen, Yuxuan Chen, Yaqi Li, Mengyun Yuan, Jian Wu, Qingmin Sun
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayProtein kinase BProgrammed cell deathCell biologyNobiletinBECN1BiologyChemistryCancer cellCell growthApoptosisCancer researchSignal transductionBiochemistryCancerFlavonoidAntioxidantGeneticsBioactive Compounds in PlantsGinger and Zingiberaceae researchGinkgo biloba and Cashew Applications