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Therapeutic strategies for critically ill patients with COVID-19

Lei Li, Ranran Li, Zhixiong Wu, Xianghong Yang, Mingyan Zhao, Jiao Liu, Dechang Chen

2020Annals of Intensive Care142 citationsDOIOpen Access PDF

Abstract

Since the 2019 novel coronavirus disease (COVID-19) outbreak originated from Wuhan, Hubei Province, China, at the end of 2019, it has become a clinical threat to the general population worldwide. Among people infected with the novel coronavirus (2019-nCoV), the intensive management of the critically ill patients in intensive care unit (ICU) needs substantial medical resource. In the present article, we have summarized the promising drugs, adjunctive agents, respiratory supportive strategies, as well as circulation management, multiple organ function monitoring and appropriate nutritional strategies for the treatment of COVID-19 in the ICU based on the previous experience of treating other viral infections and influenza. These treatments are referable before the vaccine and specific drugs are available for COVID-19.

Topics & Concepts

MedicineIntensive care medicineCoronavirus disease 2019 (COVID-19)Intensive care unitAnesthesiologyCritically illOutbreakIntensive carePopulationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DiseaseInfectious disease (medical specialty)VirologyEnvironmental healthInternal medicineAnesthesiaCOVID-19 Clinical Research StudiesRespiratory Support and MechanismsThermal Regulation in Medicine
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