Imaging in Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome
Sherwin S. Chan, Antonio Colecchia, Rafael F. Duarte, Francesca Bonifazi, Federico Ravaioli, Jean Henri Bourhis
Abstract
Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life-threatening complication of hematopoietic cell transplantation. Early diagnosis and, subsequently, earlier intervention have been shown to be beneficial to clinical outcomes. Diagnostic criteria from the European Society for Blood and Marrow Transplantation include recommendations on the use of imaging for diagnosis. This review discusses evidence on the use of imaging in the management of VOD/SOS and how imaging biomarkers can contribute to earlier diagnosis/treatment.
Topics & Concepts
MedicineHepatic veno-occlusive diseaseComplicationDiseaseTransplantationHematopoietic stem cell transplantationIntensive care medicineRadiologySurgeryInternal medicineHematopoietic Stem Cell TransplantationTransplantation: Methods and OutcomesLiver Disease and Transplantation